UKEV Forum 2023

Everything below, is left here for legacy….

We are pleased to confirm the UKEV Forum 2023 will be live in person at Fitzwilliam College, Cambridge hosted by Dr Hannah Jackson and Dr Tim Williams and the UKEV board.

Thursday 7^th – Friday 8^th December 2023.

Our Keynote speakers are confirmed, Professor Samir EL Andaloussi (Karolinska Institute), Dr Esther Nolte-t Hoen (Utrecht University), Dr Nicole Noren Hooten (NIH) and Professor Yorgo Modis (Cambridge University)

EV detection/quantification, biomarkers, EV functions in health and disease and EV therapeutics
Short talks and lightning talks for delegates
Exhibition and talks by industrial sponsors
Early Career Training Workshop pre-main-meeting (tickets available in registration)
Conference Dinner at Trinity College, University of Cambridge
Post-dinner drinks event will be held at The Hidden Rooms Cocktail Lounge

Day

Hour

Minute

Second

Registration for one more day!

Please see at the bottom of the page for information about Travel – Note there are train strikes (updated 29/11)

Thursday 7th Dec

9:00 – 12:30: Early Careers Training Workshop (booking only)

09:00 – 09:30 Workshop Registration – Tea, coffee and pastries
09:30 – 09:40 Early Career Researcher Session – Dr Hannah Jackson – Welcome
09:40 – 10:15 Early Career Researcher Session – Dr Alice Law – EV commercialisation – an industry perspective
10:15 – 10:50 Early Career Researcher Session – Dr Jimmy Gavin – Becoming a CEO and cofounder of EVolution therapeutics
10:50 – 11:30 Early Career Researcher Session – Dr Samantha Byers – How to write a successful CV and cover letter

UKEV Forum 2023, Day 1 – 11:30 – 18:30:

11:30 – 12:30: Main Registration and Lunch
12:30 – 13:00: Plenary Speaker – Dr Samir El Andaloussi – Engineering extracellular vesicles for gene editing applications

13:00 – 13:45: Oral Presentations (EVs as biomarkers):

13:00 Abstract O1 – Hannah Beattie – Do small extracellular vesicles released from different thyroid pathologies display distinct miRNA profiles?
13:15 Abstract O2 – Elaine Dunlop – EV protein cargo has potential as a diagnostic biomarker in Tuberous Sclerosis Complex
13:30 Abstract O3 – Erika Dorado – Extracellular vesicles lipid composition: a potential source of biomarkers for breast and ovarian cancer diagnosis and prognosis

13:45 – 14:05: Lightning Talks (2 minutes)

Abstract P6 – Ricardo Figueiras – Novel method for the targeted isolation of liver-specific EVs enables in-depth proteomics discovery
Abstract P7 – Thomas Brown – Investigating the Role of Extracellular Vesicles in Prostate Cancer Metastasis to Bone
Abstract P8 – Fatma Busra Isik – Transcriptomic analysis of astrocyte origin enriched plasma EVs in Alzheimers Disease
Abstract P9 – Mahmoud Eldahshoury – The use of plant EVs as a drug delivery system
Abstract P10 – Faheem Seedat – Placental small extracellular vesicles are internalized by human pancreatic beta cells and trigger transcriptional changes in recipient cells
Abstract P12 – Ryan Pink – Pipeline For Biomarker Discovery By RNA Mutation Detection Using RNA-seq And Machine Learning Of Blood Extracellular Vesicles from Pancreatic Cancer Patients

14:05 – 14:35: Sponsor Talks – NanoFCM and Cytek
14:35 – 15:00: Coffee Break
15:00 – 15:30: Plenary Speaker – Dr Nikki Noren Hooten – Extracellular Vesicles in Aging and Age-Related Conditions

15:30 – 16:00: Oral Presentations (EVs in health and disease)

15:30 Abstract O4 – Aveen Jalal – Comparison Between Secreted and Matrix Bound Extracellular Vesicles in Mineralising Tissue
15:45 Abstract O5 – Lewis Timms – Endothelial Cell derived Extracellular Vesicles Modify Myelopoiesis

16:00 – 16:20: Lightning Talks (2 minutes)

Abstract P14 – Mark Samuels – LMTK3 regulates EV biogenesis and promotes packaging of immunomodulatory cargo into EVs
Abstract P15 – Connor Levers – The TIMP-2 microRNA regulator miR-106b-5p is highly depleted in metastatic Group 4 Medulloblastoma sEVs
Abstract P16 – Simrit Sahota – Glycan-binding by placental extracellular vesicles
Abstract P19 – Pardis Parsi – Development of loading platforms for functional and differentiated EV-mediated CRISPR/Cas9 genome editing delivery
Abstract P21 – Ashwin Jainarayanan – Activated CD4 T cells relay pro-inflammatory signals through extracellular vesicles
Abstract P23 – Scott Dillon – A new toolkit for studying matrix vesicles using bioorthogonal click chemistry and correlative light-electron microscopy

16:20 – 16:50: Sponsor Talks – ONI, Bio-techne and Analytik/ParticleMetrix
16:50 – 17:10: UKEV Annual General Meeting

17:10 – 18:30: Poster Session and Drinks Reception
19:15: Formal Dinner at Trinity College – Pre booking required
21:00 – 23:30: Post Dinner Drinks at Hidden Rooms, Jesus Lane, Cambridge – Pre booking required (free to everyone)

UKEV Forum 2023 Day 2 – Friday 8th Dec

09:00 – 09:30: Plenary Speaker – Prof Yorgo Modis – Membrane fusion and cell-to-cell RNA transfer by endogenized viral proteins

09:30 – 10:15: Oral Presentations (EVs in health and disease)

09:30 Abstract O6 – Sarah Duncan – Understanding how SEVs from cells with amplified centrosomes alter the ECM in PDAC
09:45 Abstract O7 – Georgie Thompson – Small extracellular vesicles released by cardiac fibroblasts from hypertrophic cardiomyopathy patients alter action potential of human cardiomyocytes
10:00 Abstract O8 – Jacob Leonard – A Whole Host of EV-Microbiome Interactions

10:15 – 10:35: Sponsor Talk – Beckman-Coulter and Fox Biosystems
10:35 – 11:10: Coffee Break
11:10 – 11:40: Plenary Speaker – Dr Esther Nolte-t Hoen – A mutual learning experience with extracellular vesicles and viruses

11:40 – 12:40: Oral Presentations (EVs in therapeutics)

11:40 Abstract O9 – Ewan Ross – Scalable Cell Culture for the standardised production of functional Mesenchymal Stromal Cell Extracellular Vesicles for Regenerative Medicine Applications
11:55 Abstract O10 – Ioulia Vorobieva – Enhancing EV-AAV incorporation: Insights into natural loading and exogenous binding strategies for improved gene therapy vector delivery
12:10 Abstract O11 – Zubair Ahmed Nizamudeen – Engineering EVs for CRISPR-Cas9 Gene Editing
12:25 Abstract O12 – Rahul Sanwlani – Role of dietary and probiotic extracellular vesicles in cancer progression and therapy

12:40 – 12:50: Sponsor Talk – Abbelight
12:50 – 13:00: Closing Comments & Prizes

Getting here link: https://www.fitz-events.com/getting-here – Google maps link

The What3words link to the door is: ///bets.belts.awar e

There are some planned rail strikes in the UK (updated 29/11) – for updates: National Rail

For common public transport to cambridge see: National Rail, National Express, MegaBus, Stagecoach, in town parking.

The closest Park & Ride is Madingley Road which is a 23 min walk to the venue or buses every 20 minutes taking around 12 minutes into town. Can park up to 72 hours at a charge of £10 every 24 hours managed through RingGo

Link for local accommodation: Universityrooms.com

For local information: Visit Cambridge

We look forward to seeing you in December.

Best wishes, Hannah Jackson & Tim Williams – questions to events@ukev.org.uk